Ace inhibitors and Angiotensin receptor blockers
(Captopril, enalapril, lisinopril, perindopril, ramipril, candesartan, losartan, valsartan)
ACEs and ARBs have many complex actions including reducing blood pressure, preventing heart attacks and improving the function of the heart muscle. They work by preventing the formation of a chemical produced in the kidneys that makes blood vessels contract.
The benefits you will get from this drug are not immediate, but should help control and improve symptoms of heart failure in the long term. If you respond well to this therapy we anticipate you will be on it for life. You should only be on one type of ACE inhibitor and /or one type of ARB.
Possible side effects include dizziness and light-headedness due the lowering of your blood pressure, just lie down until it passes and contact your doctor or nurse if symptoms persist. Some people find they develop a dry cough on ACE inhibitors. Kidney problems can sometimes occur but this is identified early by regular blood tests. Salt substitutes in the supermarket can also increase your level of potassium and these should be avoided.
Your GP or practice nurse should take blood samples after any increase to your drugs dose to ensure your kidneys are tolerating the drugs. Once you are stabilised on the best possible dose you will only require a blood check annually. This will either be done at the nurse clinic or by your GP.
Used to treat high blood pressure and heart failure.